Team

Leadership

Bart Henderson

Chief Executive Officer

Bart Henderson is Chief Executive Officer of Wren. Bart brings extensive experience in company-building and developing innovative medicines. Previously he was operating partner at Flagship Pioneering where he led the build-out of Harbinger Health, developing an early stage cancer detection platform with leading edge artificial intelligence and machine learning technologies. Prior to Flagship, he was CEO and co-founder of Torque (now Repertoire Immune Medicines) where, under his leadership, the company significantly advanced its cellular immunotherapy pipeline, initiating the company’s first clinical trial, receiving Fast Track designation from the FDA, and building a state-of-the-art manufacturing facility for Torque’s T cell immunotherapies. Bart was founder and president of Rhythm and its subsidiary Motus which together completed successful Phase II clinical trials for two metabolic products: setmelanotide which was granted Breakthrough Designation and is the first drug approved in the US for genetic obesity; and relamorelin which was acquired by Allergan (with Motus). He was a founding employee and chief business officer of Radius, where he built the pipeline and launched the first clinical trial for Tymlos®, now approved for the treatment of osteoporosis, and acquired Elascestrant, currently in phase 3 for the treatment of metastatic breast cancer. Previously, he was an entrepreneur-in-residence at MPM Capital. He led business development at Microbia (now Ironwood Pharmaceuticals) and was head of sales and marketing at Vertex which launched its first product and significantly expanded its pipeline during his tenure. Bart previously held marketing management positions at Amgen and Merck. Bart received an M.B.A. from Dartmouth’s Tuck School of Business and a B.A. from Amherst College.

Suzanne Brewerton PhD

Head of Data & Analytics

Dr. Brewerton is Wren’s Head of Data and Analytics. Previously, she worked at AstraZeneca where she was a senior leader in the R&D IT organisation, responsible for Data, Analytics and IT strategy for Oncology and Precision Medicine. Dr. Brewerton is a proven leader with more than 20 years’ experience working with teams in data engineering, data management, software engineering and analytics, including ML and AI, across various domains such as genomics, multi-omics and structure-based drug discovery. She has led multiple, matrixed, multi-disciplinary teams in both start-ups and pharma to build data and analytics platforms and has worked and lived in both the UK and Singapore. Dr. Brewerton completed her BSc in Biochemistry at the University of Manchester during which she became interested in computational biology and analytics. She then completed her PhD in protein structural bioinformatics at the University of Cambridge, where she studied the prediction of domain boundaries, repeating motifs and unstructured regions in proteins.

Johnny Habchi PhD

Head of Research

Dr. Habchi is a Founder and Head of Research for Wren. Previously, he worked at the Centre for Misfolding Diseases, Cambridge, where his research focused on developing new methodologies in drug discovery for protein aggregation. Dr. Habchi's research included the first proof-of-principle studies demonstrating the mechanism of action of a small molecule drug targeting the misfolding and aggregation process, driven by a conceptual shift from structure-based to kinetics-based drug discovery in protein misfolding diseases. Dr. Habchi completed his BSc in Biochemistry at the Lebanese University during which he became interested in understanding the protein folding process. He then obtained masters and doctoral degrees in protein science from Aix-Marseille University, France, where he studied the folding of unstructured (intrinsically disordered) proteins. Dr. Habchi has co-authored more than 40 publications, is a Cambridge University Fellow in Leadership and a Fellow at Hughes Hall College, Cambridge.

Bochong Li PhD

Vice President, Innovation

Alleyn Plowright PhD

Head of Translational Science & Preclinical Research

Luke Rajah PhD

Head of Business Operations & Strategic Initiatives

Discovery

Alleyn Plowright PhD

Head of Translational Science & Preclinical Research

Kerry Jenkins PhD

Director, Medicinal Chemistry

Andrew Cridland PhD

Medicinal Chemistry

Bill Tatsis PhD

Computational Chemistry

Technology Platform

Suzanne Brewerton PhD

Head of Data & Analytics

Johnny Habchi PhD

Head of Research

Shimobi Onuoha PhD

Director, Biologics

Benedetta Mannini PhD

Principal Scientist, Translational Models

Michele Perni PhD

Principal Scientist, Translational Models

Xiaoting Yang PhD

Principal Scientist, Protein Biochemistry

Business Operations

Luke Rajah PhD

Head of Business Operations & Strategic Initiatives

Michal Cabadaj

Senior Director, Business Development

Bochong Li PhD

Vice President, Innovation

Gemma Marlow

Head of Human Resources & Administration

Luke Rajah PhD

Head of Business Operations & Strategic Initiatives

Joe Wilson

Finance Director