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More than 50 human protein misfolding diseases have been described to date.

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Neurological

Non-neurological localized

Systemic

Alzheimer's disease Type II diabetes  AL amyloidosis
Parkinson's disease Inclusion-body myositis AH amyloidosis
Dementia with Lewy bodies Pulmonary alveolar proteinosis AA amyloidosis
Frontotemporal dementia Lattice corneal dystrophy Familial Mediterranean fever
Amyotrophic lateral sclerosis Dry AMD Senile systemic amyloidosis
Huntington's disease Glaucoma Transthyretin amyloidosis
Spongiform encephalopathies (including CJF, FFI, GSS) Cataract Dialysis-related amyloidosis
Spinocerebellar atazias Atrial amyloidosis ApoAI amyloidosis
Spinal and bulbar muscular atrophy Aortic medial amyloidosis ApoAII amyloidosis
Hereditary dentatorubral-pallidoluysian atrophy Thyroid medullary carcinoma ApoAIV amyloidosis
Familial British dementia HCHWA Finish hereditary amyloidosis
Familial Danish dementia Pituitary prolactinoma Lysozyme amyloidosis
CADASIL syndrome Injection-localized amyloidosis Fibrinogen amyloidosis
Alexander's disease Trichiasis corneal amyloidosis Icelandic hereditary cerebral amyloid angiopathy
Cerebral amyloid angiopathy Cutaneous lichen amyloidosis Fabry disease
  Retinitis pigmentosa Gaucher's disease
   Cystic fibrosis α-Antitrypsin deficiency
  Nephrogenic diabetes insipidus  

 

 

Neurological

Non-neurological localized

Systemic

Alzheimer's disease Type II diabetes  AL amyloidosis
Parkinson's disease Inclusion-body myositis AH amyloidosis

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